Columbia University

Technology Ventures

Chiesi Global Rare Diseases Request for Proposals

Deadline: 
Monday, May 30, 2022 - 5:00pm

Chiesi Global Rare Diseases is seeking research proposals for new technologies from academic medical centers, universities, and research institutions globally for technologies to address distribution of macromolecules in hard-to-reach tissues

Pre-Proposal Deadline: May 30, 2022. Please reach out to your CTV licensing officer before submitting a pre-proposal.

Collaborating with Chiesi
We look forward to hearing from researchers and physicianscientists who are keen to collaborate with a global pharma company with a strong track record of translational R&D in rare diseases. 

Our objective is to award funds to validate early-stage projects with clear therapeutic potential. Successful applicants will be funded through sponsored research, with up to $275K/€250K available per project for 2 years duration. This should enable researchers to generate relevant pre-clinical data or demonstrate preclinical proof of concept for technologies enabling effective biodistribution of macromolecules (for example: nucleic acids, proteins) to the following tissues of interest, characterized by challenges in delivery (any or all):
• Bone
• Skeletal/cardiac muscle
• Central nervous system
for the treatment of rare metabolic diseases, for example inborn errors of metabolism, including lysosomal storage disorders. The technology might be brought into the Chiesi Global Rare Diseases  pipeline and ultimately benefit patients.

What We Are Looking For
We are seeking new technologies with key attributes including some of the following:
1. Potential for platform development (for example to address multiple indications)
2. Preliminary pre-clinical evidence to support feasibility of technology
3. Innovative models for technology validation (e.g. organoids)
4. Strong potential for clinical impact

Therapeutic Areas of Interest for 2022
Delivery technologies that can be applied to the treatment of rare metabolic diseases, for example inborn errors of metabolism, including lysosomal storage disorders.

Proposal Submission Process
The first step in the process is submission of a Pre-Proposal which should contain a brief, non-confidential 2-3 page overview of the target, mechanism (including evidence for link to disease), and the proposed therapeutic opportunity. A more detailed Full Proposal will be solicited by invitation only.

More Information
For inquiries please contact: [email protected]
All investigators whose work meets these requirements are encouraged to apply.
Please download the Pre-Proposal template and submit completed applications by May 30, 2022. Please reach out to your CTV licensing officer before submitting a pre-proposal.