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Widespread Dopamine Deficits Found in Brains of Patients with Schizophrenia (CUMC Newsroom)

Source: CUMC Newsroom

Columbia researchers have found evidence of reduced levels of the transmitter dopamine in the frontal cortex of patients with schizophrenia. This deficit, which affects the ability of the frontal cortex to become activated when subjects are faced with cognitive demands such as memory tasks, is most likely responsible for the cognitive deficits seen in patients with schizophrenia. The study was published online today in JAMA Psychiatry.